Cord Blood Stem Cells in Treating Polycystic Kidney Disease

According to sources of stem cells, cord blood stem cells belong to somatic stem cells, while they are also pluripotent stem cells in comparing the differentiating potential of stem cells. The main functions of stem cells are able to rebuild blood system and immune system. The renal damage caused by Polycystic Kidney Disease (PKD) is mainly attributed to the immune inefficiencyand the severe lack of blood and oxygen in kidney. Thus cord blood stem cells are destined to play an important role in treating Polycystic Kidney Disease.
Rebuilding blood systems
Cord blood stem cells are biologically younger and have unique qualities than other stem cells. Umbilical cord is the access between a mother and her baby before being born. Though umbilical cord, the baby absorbs nutrients form its mother. The carrier of nutrients is cord blood, which provides all necessary substances for the growth of the baby. So the cord blood stem cells own the great ability of developing into red blood cells, white blood cells and soterocyte. If they are transplanted in to the body of patient with PKD, those stem cells can rebuild the blood systems in kidney ease the lack of blood and oxygen and greatly improve microcirculation, avoiding the further damage of kidneys. It is common that the look of those who have received stem cell transplantation will turn better than before, because edema has been greatly eased.
Strengthening immune system
As we just mentioned above, cord blood provides the baby with all materials to build its organs and systems. In fact, the baby is born with immune system, but its immune system has not matured, needing to strengthen. Therefore, cord blood stem cells have the potential to develop in to the cells of immune system. In addition, they are capable to secrete some nutrients, maturing or strengthening immune system. Patients with PKD usually have immune inefficiency in the late stages, which means they are easily infected or their renal cells are unusual sensitive. Infections are the main cause of PKD deteriorating into renal damages or renal failure. Cord blood stem cells boast for rebuilding the power of patients’ immunity to guard against virus or bacteria invading.
Polycystic Kidney Disease may be less dangerous than its complications, such as high blood pressure, renal failure, heart failure and stroke, which mainly result from the cysts suppress other renal tissues in lack of blood and oxygen. The blood system and immune system in kidney are destroyed. Cord blood stem cells transplantation is to rebuild those two systems to reduce the damage made by PKD.
In addition, cord blood stem cells are taken from the abandoned cord after the baby being born, without harming the mother and her baby. The transplantation is not involved in moral issue. It has a bright future in treating Polycystic Kidney Disease.

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