Symptoms of renal hypertension

Hypertension, renal hypertension symptoms also exists , not repeat them. Here are just some of the special aspects of the performance of renal hypertension make a profile .
Compared with the same level of essential hypertension, renal hypertension essential hypertension compared with more progress to malignant hypertension , which occurs in approximately 2 -fold. Which , IgA nephropathy , especially sclerosis , or hardening of IgA nephropathy secondary to malignant hypertension , especially common. Also, comparison with primary malignant hypertension , renal parenchymal malignant hypertension worse prognosis , some authors statistics , the former five-year kidney survival rate was 60%, while the latter one and a half years renal survival is only 4 %.
Renal hypertension is often severe retinopathy , cardiovascular and cerebrovascular complications occur more often . This is because in addition to hypertension, other cardiovascular risk factors often compound the presence of renal parenchymal disease, such as lipid metabolism disorder nephrotic syndrome , and glucose metabolism during diabetic nephropathy , anemia, renal insufficiency , and hyperuricemia disease, high homocysteine ​​, uremic toxins, metabolic acidosis , and micro- inflammatory state , these complex factors will significantly increase the incidence of cardiovascular complications.
In this , the need to emphasize that especially affect renal hypertension and chronic kidney disease on the basis of renal disease progression . Chronic renal disease was before the glomerular arterioles diastolic state, the system is very easy to pass the glomerular hypertension , resulting in glomerular hypertension, high perfusion and high filtration, this "three high " that can accelerate the remaining glomerulosclerosis ; Meanwhile , long-term high blood pressure can lead to kidney arteriosclerosis , including hyaline afferent arterioles , interlobular artery and arcuate artery intimal thickening of the muscle , so that small artery wall thickening luminal narrowing , secondary to renal ischemia
Damage ( glomerular ischemic collapse was to ischemic sclerosis , tubular atrophy and renal interstitial fibrosis ) . Therefore, renal hypertension is not well controlled will significantly accelerate renal parenchymal disease progression , creating a vicious cycle .

Urinary protein quantity glomerular disease , hypertension and kidney damage effect is more obvious , because both effects overlay. Now known proteinuria, especially in a large number of glomerular proteinuria can be caused by a high pressure, high perfusion and high filtration promote glomerulosclerosis ; And, filtered proteins ( including complement and growth factors , etc.) and in combination with protein certain substances ( including lipid and iron, etc. ) after being tubular reabsorption , tubular cells can activate the release of pathogenic factors ( such as transforming growth factor β , etc. ) to promote renal interstitial fibrosis. Therefore, in patients with renal hypertension with proteinuria , more should be strictly controlled hypertension.